Adaptive design methods in clinical trails

Adaptive design methods in clinical trails

by Shein-chung Chow
2/5
(2 votes)

Although adaptive design methods are flexible and useful in clinical research, little or no regulatory guidelines are available.

One of the first books on the topic, Adaptive Design Methods in Clinical Trials presents the principles and m.

Format
277 pages, Hardcover
First published
2005
Publishers
Chapman & Hall/CRC
Language
English

I used this book and accompanying software for about a year and was surprised, when opening the software, to be greeted with the message, "Your license will expire within 30 days. Please contact license@[...

This book's best features are its bibliography (about 240 entries) and its broad survey and taxonomy of adaptive methods. Its publication represents an important step in popularizing adaptive trials and, thus, streamlining drug/device/biologic development pipelines.

I meet the second author, Mark Chang, at a conference on adaptive designs. I work as a professional statistician in the pharmaceutical industry.

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